How Vibrent’s platform powered the most diverse, digital-first cohort in US history—and what it means for UK’s registries
Problem:
UK registries face major systemic challenges:
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Mission of registries is not fulfilled patient advocacy, patient support/education and research
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Limited representation of ethnic, rural, and underserved populations
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Fragmented tools and siloed data
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Manual recruitment and paper-based consent
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Low retention
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Inability to collect real-world data at scale (e.g., EHRs, wearables, SDoH)
These challenges mirror the ones faced in the US prior to the launch of the NIH’s All of Us Research Program.
Solution:
Vibrent’s Digital Health Research Platform:
Vibrent served as the technology backbone for the All of Us Program, delivering:
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Web and mobile enrollment + multilingual eConsent
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Automated digital outreach (SMS, email, in-app)
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Seamless real-world data collection (EHRs, genomics, biospecimens, wearables, surveys)
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Integrated dashboards for researchers, study staff, and
cohort analytics -
Secure cloud infrastructure: HIPAA, GDPR, DTAC, Cyber
Essentials Plus, NHS ethics-ready
Results
Over
848,000
Participants Enrolled
87%
From Underrepresented Backgrounds
310,000
Records from Wearable Data
2.5 Million
eConsent
13 Million
Surveys/PROS/QoLs
134 Million
Patient Engagements
Traditional vs. Digital-First Model Comparison
Impact Metrics + Registry Alignment
Key Metrics from All of Us (as of 2024)
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Participants enrolled: 848,783
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Underrepresented minorities: 87%
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Rural participants: 58,000
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Sexual & gender minorities: 52,000
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eConsent modules completed: 2,015,622
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EHR records integrated: 14,431
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Fitbit / Apple HealthKit connections: 49,627 / 19,940
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Survey modules completed: 3.6 million+
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Automated SMS / email messages: 72.6 million
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Study staff time saved (per FTE/year): ~624 hours
Why This Matters for UK Registry Leaders
UK health strategy is shifting toward:
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Fulfill the mission of registries by providing patient advocacy, patient support/education and research
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Decentralised research in communities and homes
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Better inclusion of underserved populations
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Collection of Real-World Data – integration with EHR and public datasets and genomics data
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Create Real-World Evidence that can help advances therapies, cures and drug development
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Digital-first, prevention-oriented care
Vibrent’s platform offers UK registries:
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GDPR, NHS DTAC, Cyber Essentials Plus certified, HRA ethics compliance
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Interoperability with NHS trusts and community networks
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A way to build registries faster, cheaper, and more inclusively
